Our research programs focus on the immune system and its pathologies and regroup most investigators involved in this field on the Bordeaux campus.

The immune system is dedicated to preserve the host integrity. When the latter is threatened by environmental pathogens or by abnormal cell growth or stresses, different natural defenses are mobilized to maintain a steady state. However, infectious micro-organisms have evolved adaptive strategies to evade from this immune response. Similarly, cancer development results in part from tumor-induced immunosuppression and immune escape. Conversely, in the case of auto-immune diseases, the immune system itself is dysfunctional and overactivated in relation with yet unknown genetic and/or environmental causes. In organ or stem cell transplantation, uncontrolled immune activation leads to tissue damage or graft rejection. In all these situations, T lymphocytes are key elements to either maintain integrity through effector or regulatory functions, or to enhance pathogenicity.
Consequently, modulation of T cell activation is a general concern in the prevention or cure of various diseases including cancer, infections, autoimmune disorders, graft rejection or graft-versus-host disease. The delineation of the mechanisms underlying this activation is a prerequisite towards this goal. In this context, the global objective of our team since several years is to understand the cellular and molecular mechanisms of human T lymphocyte activation in normal or pathological conditions. A special focus is made on gamma-delta T lymphocytes, on autoimmune diseases and cancer two topics on which our members have developed an expertise, important tools and national and international collaborations since many years.
Our research aims to shed light on the question of how an immune response against foreign or self-antigens can lead to either protective immunity (against CMV or tumors or in surveillance of cell stress), to control of homeostasis (surveillance of tissue integrity) or to breakdown of tolerance (in autoimmunity or transplantation). Imental for optimal development of our studies.

PUBLICATIONS

2019

Goutaudier, V., H. Perrochia, S. Mucha, M. Bonnet, S. Delmas, F. Garo, V. Garrigue, S. Lepreux, V. Pernin, J. E. Serre, I. Szwarc, P. Merville, A. Ramounau-Pigot, C. Rene, J. Visentin, B. P. Morgan, V. Fremeaux-Bacchi, G. Mourad, L. Couzi and M. Le Quintrec (2019). “C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection.” Front Immunol 10: 235.

Tumiotto, C., B. M. Alves, P. Recordon-Pinson, M. Jourdain, P. Bellecave, G. L. Guidicelli, J. Visentin, F. Bonnet, M. Hessamfar, D. Neau, J. Sanchez, C. Brander, M. Sajadi, L. Eyzaguirre, E. A. Soares, J. P. Routy, M. A. Soares and H. Fleury (2019). “Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles.” PLoS One 14(2): e0212347.

Cargou, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-A*33:170 allele by sequencing-based typing.” HLA 93(4): 221-223.

Cargou, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DPB1*896:01 allele by sequencing-based typing.” HLA 93(4): 246-247.

Cargou, M., M. Andreani, M. Troiano, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DQA1*05:14 allele by sequencing-based typing.” HLA 93(4): 241-243.

Cargou, M., M. Andreani, M. Battarra, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-C*07:708 allele by sequencing-based typing.” HLA 93(4): 235-236.

Delville, M., B. Lamarthee, S. Pagie, S. B. See, M. Rabant, C. Burger, P. Gatault, M. Giral, O. Thaunat, N. Arzouk, A. Hertig, M. Hazzan, M. Matignon, C. Mariat, S. Caillard, N. Kamar, J. Sayegh, P. F. Westeel, C. Garrouste, M. Ladriere, V. Vuiblet, J. Rivalan, P. Merville, D. Bertrand, A. Le Moine, J. P. D. Van Huyen, A. Cesbron, N. Cagnard, O. Alibeu, S. C. Satchell, C. Legendre, E. Zorn, J. L. Taupin, B. Charreau and D. Anglicheau (2019). “Early Acute Microvascular Kidney Transplant Rejection in the Absence of Anti-HLA Antibodies Is Associated with Preformed IgG Antibodies against Diverse Glomerular Endothelial Cell Antigens.” J Am Soc Nephrol 30(4): 692-709.

Di Lorenzo, B., A. E. Simoes, F. Caiado, P. Tieppo, D. V. Correia, T. Carvalho, M. G. da Silva, J. Dechanet-Merville, T. N. Schumacher, I. Prinz, H. Norell, S. Ravens, D. Vermijlen and B. Silva-Santos (2019). “Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells.” Cancer Immunol Res 7(4): 552-558.

Gaillard, F., M. Courbebaisse, N. Kamar, L. Rostaing, L. Jacquemont, M. Hourmant, A. Del Bello, L. Couzi, P. Merville, P. Malvezzi, B. Janbon, B. Moulin, N. Maillard, L. Dubourg, S. Lemoine, C. Garrouste, H. Pottel, C. Legendre, P. Delanaye and C. Mariat (2019). “Impact of estimation versus direct measurement of predonation glomerular filtration rate on the eligibility of potential living kidney donors.” Kidney Int 95(4): 896-904.

Ralazamahaleo, M., M. Andreani, T. Galluccio, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DRB3*03:01:07 allele by sequencing-based typing.” HLA 93(4): 240-241.

Venot, Q., T. Blanc, S. H. Rabia, L. Berteloot, S. Ladraa, J. P. Duong, E. Blanc, S. C. Johnson, C. Hoguin, O. Boccara, S. Sarnacki, N. Boddaert, S. Pannier, F. Martinez, S. Magassa, J. Yamaguchi, B. Knebelmann, P. Merville, N. Grenier, D. Joly, V. Cormier-Daire, C. Michot, C. Bole-Feysot, A. Picard, V. Soupre, S. Lyonnet, J. Sadoine, L. Slimani, C. Chaussain, C. Laroche-Raynaud, L. Guibaud, C. Broissand, J. Amiel, C. Legendre, F. Terzi and G. Canaud (2019). “Author Correction: Targeted therapy in patients with PIK3CA-related overgrowth syndrome.” Nature 568(7752): E6.

Visentin, J., D. L. Leu, A. Mulder, F. Jambon, L. Badier, J. H. Lee, G. Guidicelli, C. Bouthemy, M. Ralazamahaleo, F. Claas, C. Di Primo and J. L. Taupin (2019). “Measuring anti-HLA antibody active concentration and affinity by surface plasmon resonance: Comparison with the luminex single antigen flow beads and T-cell flow cytometry crossmatch results.” Mol Immunol 108: 34-44.

Elsermans, V., J. Visentin, I. Top, P. Varlet and M. Labalette (2019). “Characterization of the novel HLA-DRB1*14:207 allele by sequencing-based typing.” HLA.

Elsermans, V., J. Visentin, I. Top, P. Varlet and M. Labalette (2019). “Characterization of the novel HLA-DQB1*03:353 allele by sequencing-based typing.” HLA.

Elsermans, V., J. Visentin, I. Top, P. Varlet and M. Labalette (2019). “Characterization of the novel HLA-B*07:02:73 allele by sequencing-based typing.” HLA.

Elsermans, V., J. Visentin, I. Top, P. Varlet and M. Labalette (2019). “Characterization of the novel HLA-C*07:724 allele by sequencing-based typing.” HLA.

Glotz, D., G. Russ, L. Rostaing, C. Legendre, G. Tufveson, S. Chadban, J. Grinyo, N. Mamode, P. Rigotti, L. Couzi, M. Buchler, S. Sandrini, B. Dain, M. Garfield, M. Ogawa, T. Richard, W. H. Marks and C. s. group (2019). “Safety and efficacy of eculizumab for the prevention of antibody-mediated rejection after deceased-donor kidney transplantation in patients with preformed donor-specific antibodies.” Am J Transplant.

Meunier, P., L. Dequidt, T. Barnetche, E. Lazaro, P. Duffau, C. Richez, L. Couzi, M. E. Truchetet, J. Seneschal and A. Fhu (2019). “Increased risk of mortality in systemic sclerosis-associated digital ulcers: a systematic review and meta-analysis.” J Eur Acad Dermatol Venereol 33(2): 405-409.

Sommerer, C., B. Suwelack, D. Dragun, P. Schenker, I. A. Hauser, O. Witzke, C. Hugo, N. Kamar, P. Merville, M. Junge, F. Thaiss, B. Nashan and G. Athena Study (2019). “An open-label, randomized trial indicates that everolimus with tacrolimus or cyclosporine is comparable to standard immunosuppression in de novo kidney transplant patients.” Kidney Int.

Cargou, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-A*03:315 allele by sequencing-based typing.” HLA 93(1): 39-40.

Cargou, M., M. Ralazamahaleo, L. Blouin, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DQA1*04:05 allele by sequencing-based typing.” HLA 93(1): 59-60.

Cargou, M., M. Ralazamahaleo, L. Blouin, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-A*30:135 allele by sequencing-based typing.” HLA 93(1): 46-47.

Cargou, M., M. Ralazamahaleo, L. Blouin, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DRB5*02:21 allele by sequencing-based typing.” HLA 93(1): 58-59.

Cargou, M., M. Ralazamahaleo, L. Blouin, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DPA1*02:12 allele by sequencing-based typing.” HLA 93(1): 61-62.

Elsermans, V., J. Visentin, I. Top, M. Labalette and P. Varlet (2019). “Characterization of the novel HLA-DRB1*13:191 allele by sequencing-based typing.” HLA 93(1): 55-56.

Elsermans, V., J. Visentin, I. Top, P. Varlet and M. Labalette (2019). “Characterization of the novel HLA-C*03:302 allele by sequencing-based typing.” HLA 93(1): 51-52.

Ralazamahaleo, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2019). “Characterization of the novel HLA-DRB1*03:147 allele by sequencing-based typing.” HLA 93(1): 53-54.

Scherlinger, M., C. Carcaud, M. E. Truchetet, T. Barnetche, P. Duffau, L. Couzi, J. Seneschal, P. Blanco, E. Lazaro and C. Richez (2019). “Rituximab in moderate to severe non-renal systemic lupus erythematosus: a reanalysis of the EXPLORER study.” Ann Rheum Dis.

Domblides, C., L. Lartigue and B. Faustin (2019). “Control of the Antitumor Immune Response by Cancer Metabolism.” Cells 8(2).

Prezelin-Reydit, M., C. Combe, J. Harambat, C. Jacquelinet, P. Merville, L. Couzi and K. Leffondre (2019). “Prolonged dialysis duration is associated with graft failure and mortality after kidney transplantation: results from the French transplant database.” Nephrol Dial Transplant 34(3): 538-545.

Snanoudj, R., N. Kamar, E. Cassuto, S. Caillard, M. Metzger, P. Merville, A. Thierry, I. Jollet, P. Grimbert, D. Anglicheau, M. Hazzan, G. Choukroun, B. Hurault De Ligny, B. Janbon, V. Vuiblet, A. Devys, Y. Le Meur, M. Delahousse, E. Morelon, E. Bailly, S. Girerd, K. Amokrane, C. Legendre, A. Hertig, E. Rondeau and J. L. Taupin (2019). “Epitope load identifies kidney transplant recipients at risk of allosensitization following minimization of immunosuppression.” Kidney Int.

Audemard-Verger, A., E. Pillebout, A. Jamin, L. Berthelot, C. Aufray, B. Martin, A. Sannier, E. Daugas, J. Dechanet-Merville, Y. Richard, R. Monteiro and B. Lucas (2019). “Recruitment of CXCR3(+) T cells into injured tissues in adult IgA vasculitis patients correlates with disease activity.” J Autoimmun 99: 73-80.

McCarthy, L. M., J. D. Visentin and P. A. Rochon (2019). “Assessing the Scope and Appropriateness of Prescribing Cascades.” J Am Geriatr Soc 67(5): 1023-1026.

2018

Howard, J., I. Zaidi, S. Loizon, O. Mercereau-Puijalon, J. Dechanet-Merville and M. Mamani-Matsuda (2018). “Human Vgamma9Vdelta2 T Lymphocytes in the Immune Response to P. falciparum Infection.” Front Immunol 9: 2760.

Queirolo, P., B. Dozin, A. Morabito, B. Banelli, P. Piccioli, C. Fava, C. Leo, R. Carosio, S. Laurent, V. Fontana, P. F. Ferrucci, C. Martinoli, E. Cocorocchio, A. Battaglia, P. A. Ascierto, M. Capone, E. Simeone, F. De Galitiis, E. Pagani, G. C. Antonini Cappellini, P. Marchetti, M. Guida, S. Tommasi, M. Mandala, B. Merelli, P. Quaglino, P. Fava, M. Guidoboni, M. Romani, F. Spagnolo and M. P. Pistillo (2018). “Corrigendum: Association of CTLA-4 Gene Variants with Response to Therapy and Long-term Survival in Metastatic Melanoma Patients Treated with Ipilimumab: An Italian Melanoma Intergroup Study.” Front Immunol 9: 403.
[This corrects the article on p. 386 in vol. 8, PMID: 28446908.].

Guidicelli, G., V. Elsermans, I. Top, M. Ralazamahaleo and J. Visentin (2018). “Characterization of the novel HLA-A*24:391 allele by sequencing-based typing.” HLA 91(4): 292-293.

Guidicelli, G., V. Elsermans, I. Top, M. Ralazamahaleo and J. Visentin (2018). “Characterization of the novel HLA-C*16:116 allele by sequencing-based typing.” HLA 91(4): 309-311.

Guidicelli, G., V. Elsermans, I. Top, M. Ralazamahaleo and J. Visentin (2018). “Characterization of the novel HLA-B*07:305 allele by sequencing-based typing.” HLA 91(4): 296-297.

Courant, M., J. Visentin, G. Linares, V. Dubois, S. Lepreux, G. Guidicelli, O. Thaunat, P. Merville, L. Couzi and J. L. Taupin (2018). “The disappointing contribution of anti-human leukocyte antigen donor-specific antibodies characteristics for predicting allograft loss.” Nephrol Dial Transplant.

Bouthemy, C., M. Ralazamahaleo, I. Jollet, M. Filloux, J. Visentin and G. Guidicelli (2018). “Improvement in HLA-typing by new sequence-specific oligonucleotides kits for HLA-A, -B and -DRB1 loci.” HLA.

Cargou, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2018). “Characterization of the novel HLA-DPB1*763:01 allele by sequencing-based typing.” HLA 92(6): 429-431.

Cargou, M., M. Ralazamahaleo, L. Blouin, G. Guidicelli and J. Visentin (2018). “Characterization of the novel HLA-C*07:639 allele by sequencing-based typing.” HLA 92(6): 422-423.

Ralazamahaleo, M., V. Elsermans, I. Top, G. Guidicelli and J. Visentin (2018). “Characterization of the novel HLA-B*15:476 allele by sequencing-based typing.” HLA 92(6): 412-413.

Vincenti, F., K. Budde, P. Merville, F. Shihab, V. Ram Peddi, M. Shah, K. Wyburn, E. Cassuto-Viguier, A. Weidemann, M. Lee, T. Flegel, J. Erdman, X. Wang and C. Lademacher (2018). “A randomized, phase 2 study of ASP0113, a DNA-based vaccine, for the prevention of CMV in CMV-seronegative kidney transplant recipients receiving a kidney from a CMV-seropositive donor.” Am J Transplant 18(12): 2945-2954.

Jacquemin, C., J. F. Augusto, M. Scherlinger, N. Gensous, E. Forcade, I. Douchet, E. Levionnois, C. Richez, E. Lazaro, P. Duffau, M. E. Truchetet, J. Seneschal, L. Couzi, J. L. Pellegrin, J. F. Viallard, T. Schaeverbeke, V. Pascual, C. Contin-Bordes and P. Blanco (2018). “OX40L/OX40 axis impairs follicular and natural Treg function in human SLE.” JCI Insight 3(24).

Di Primo, C., J. L. Taupin and J. Visentin (2018). “Comments on “Direct quantitative measurement of the kinetics of HLA-specific antibody interactions with isolated HLA proteins”.” Hum Immunol 79(2): 129.

Guidicelli, G., J. L. Taupin and J. Visentin (2018). “Predicted indirectly recognizable HLA epitopes (PIRCHE): Only the tip of the iceberg?Am J Transplant 18(2): 521-522.

Glotz, D., L. Rostaing, P. Merville, J. P. Squifflet and Y. Lebranchu (2018). “Intravenous Immunoglobulins in the Prevention of Rejection of a Second or Third Kidney Graft.” Transplant Proc 50(1): 70-71.

Clement, J., B. Taton, P. Merville, J. F. Viallard, E. Lazaro, L. Couzi and E. Riviere (2018). “Two cases of tacrolimus-induced neutropenia: A probably under-diagnosed cause of neutropenia after solid-organ transplantation.” Clin Transplant 32(7): e13295.

Guidicelli, G., J. Visentin, N. Franchini, C. Borg, P. Merville, L. Couzi and J. L. Taupin (2018). “Prevalence, distribution and amplitude of the complement interference phenomenon in single antigen flow beads assays.” HLA 91(6): 507-513.

Venot, Q., T. Blanc, S. H. Rabia, L. Berteloot, S. Ladraa, J. P. Duong, E. Blanc, S. C. Johnson, C. Hoguin, O. Boccara, S. Sarnacki, N. Boddaert, S. Pannier, F. Martinez, S. Magassa, J. Yamaguchi, B. Knebelmann, P. Merville, N. Grenier, D. Joly, V. Cormier-Daire, C. Michot, C. Bole-Feysot, A. Picard, V. Soupre, S. Lyonnet, J. Sadoine, L. Slimani, C. Chaussain, C. Laroche-Raynaud, L. Guibaud, C. Broissand, J. Amiel, C. Legendre, F. Terzi and G. Canaud (2018). “Targeted therapy in patients with PIK3CA-related overgrowth syndrome.” Nature 558(7711): 540-546.

Meunier, P., L. Dequidt, T. Barnetche, E. Lazaro, P. Duffau, C. Richez, L. Couzi, M. E. Truchetet, J. Seneschal and A. Fhu (2018). “Increased risk of mortality in systemic sclerosis-associated digital ulcers: a systematic review and meta-analysis.” J Eur Acad Dermatol Venereol.

Courant, M., J. Visentin, G. Linares, V. Dubois, S. Lepreux, G. Guidicelli, O. Thaunat, P. Merville, L. Couzi and J. L. Taupin (2018). “Erratum.” Nephrol Dial Transplant.

Domblides, C., L. Lartigue and B. Faustin (2018). “Metabolic Stress in the Immune Function of T Cells, Macrophages and Dendritic Cells.” Cells 7(7).

Prezelin-Reydit, M., C. Combe, J. Harambat, C. Jacquelinet, P. Merville, L. Couzi and K. Leffondre (2018). “Prolonged dialysis duration is associated with graft failure and mortality after kidney transplantation: results from the French transplant database.” Nephrol Dial Transplant.

Nguyen, Q. L., P. Merville and L. Couzi (2018). “Impact of the individualized risks of end-stage renal disease on living kidney donor selection.” Nephrol Dial Transplant.

Arbore, G., E. E. West, J. Rahman, G. Le Friec, N. Niyonzima, M. Pirooznia, I. Tunc, P. Pavlidis, N. Powell, Y. Li, P. Liu, A. Servais, L. Couzi, V. Fremeaux-Bacchi, L. Placais, A. Ferraro, P. R. Walsh, D. Kavanagh, B. Afzali, P. Lavender, H. J. Lachmann and C. Kemper (2018). “Complement receptor CD46 co-stimulates optimal human CD8(+) T cell effector function via fatty acid metabolism.” Nat Commun 9(1): 4186.

Visentin, J., L. Couzi, C. Dromer, M. Neau-Cransac, G. Guidicelli, V. Veniard, K. N. Coniat, P. Merville, C. Di Primo and J. L. Taupin (2018). “Overcoming non-specific binding to measure the active concentration and kinetics of serum anti-HLA antibodies by surface plasmon resonance.” Biosens Bioelectron 117: 191-200.

Gaillard, F., M. Courbebaisse, N. Kamar, L. Rostaing, A. Del Bello, S. Girerd, M. Kessler, M. Flamant, E. Vidal-Petiot, M. N. Peraldi, L. Couzi, P. Merville, P. Malvezzi, B. Janbon, B. Moulin, S. Caillard, P. Gatault, M. Buchler, N. Maillard, L. Dubourg, O. Roquet, C. Garrouste, C. Legendre, P. Delanaye and C. Mariat (2018). “The age-calibrated measured glomerular filtration rate improves living kidney donation selection process.” Kidney Int 94(3): 616-624.

2017

Khairallah, C., J. Dechanet-Merville and M. Capone (2017). “gammadelta T Cell-Mediated Immunity to Cytomegalovirus Infection.” Front Immunol 8: 105.

Lawand, M., J. Dechanet-Merville and M. C. Dieu-Nosjean (2017). “Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications.” Front Immunol 8: 761.

Visentin, J., G. Guidicelli and J. L. Taupin (2017). “Conformational Variants of HLA-I Antigens on Luminex Single Antigen Beads.” Transplantation 101(4): e152-e153.

Thilly, N., J. Chanliau, L. Frimat, C. Combe, P. Merville, P. Chauveau, P. Bataille, R. Azar, D. Laplaud, C. Noel and M. Kessler (2017). “Cost-effectiveness of home telemonitoring in chronic kidney disease patients at different stages by a pragmatic randomized controlled trial (eNephro): rationale and study design.” BMC Nephrol 18(1): 126.

Mourad, G., M. Glyda, L. Albano, O. Viklicky, P. Merville, G. Tyden, M. Mourad, A. Lohmus, O. Witzke, M. H. L. Christiaans, M. W. Brown, N. Undre, G. Kazeem, D. R. J. Kuypers and i. Advagraf-based immunosuppression regimen examining new onset diabetes mellitus in kidney transplant recipients study (2017). “Incidence of Posttransplantation Diabetes Mellitus in De Novo Kidney Transplant Recipients Receiving Prolonged-Release Tacrolimus-Based Immunosuppression With 2 Different Corticosteroid Minimization Strategies: ADVANCE, A Randomized Controlled Trial.” Transplantation 101(8): 1924-1934.

Ruiz-Irastorza, G., A. Ugarte, C. Saint-Pastou Terrier, E. Lazaro, A. Iza, L. Couzi, R. Saenz, C. Richez, S. Porta and P. Blanco (2017). “Repeated pulses of methyl-prednisolone with reduced doses of prednisone improve the outcome of class III, IV and V lupus nephritis: An observational comparative study of the Lupus-Cruces and lupus-Bordeaux cohorts.” Autoimmun Rev 16(8): 826-832.

Goret, J., L. Beven, B. Faustin, C. Contin-Bordes, C. Le Roy, S. Claverol, H. Renaudin, C. Bebear and S. Pereyre (2017). “Interaction of Mycoplasma hominis PG21 with Human Dendritic Cells: Interleukin-23-Inducing Mycoplasmal Lipoproteins and Inflammasome Activation of the Cell.” J Bacteriol 199(15).

Touzot, M., C. S. Terrier, S. Faguer, I. Masson, H. Francois, L. Couzi, A. Hummel, N. Quellard, G. Touchard, N. Jourde-Chiche, J. M. Goujon, E. Daugas and R. Groupe Cooperatif sur le Lupus (2017). “Proliferative lupus nephritis in the absence of overt systemic lupus erythematosus: A historical study of 12 adult patients.” Medicine (Baltimore) 96(48): e9017.

Furman, D., J. Chang, L. Lartigue, C. R. Bolen, F. Haddad, B. Gaudilliere, E. A. Ganio, G. K. Fragiadakis, M. H. Spitzer, I. Douchet, S. Daburon, J. F. Moreau, G. P. Nolan, P. Blanco, J. Dechanet-Merville, C. L. Dekker, V. Jojic, C. J. Kuo, M. M. Davis and B. Faustin (2017). “Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.” Nat Med 23(2): 174-184.

Ghisdal, L., C. Baron, Y. Lebranchu, O. Viklicky, A. Konarikova, M. Naesens, D. Kuypers, M. Dinic, E. Alamartine, G. Touchard, T. Antoine, M. Essig, J. P. Rerolle, P. Merville, J. L. Taupin, Y. Le Meur, A. Grall-Jezequel, F. Glowacki, C. Noel, C. Legendre, D. Anglicheau, N. Broeders, W. Coppieters, E. Docampo, M. Georges, Z. Ajarchouh, A. Massart, J. Racape, D. Abramowicz and M. Abramowicz (2017). “Genome-Wide Association Study of Acute Renal Graft Rejection.” Am J Transplant 17(1): 201-209.

Monlun, M., C. Hyernard, P. Blanco, L. Lartigue and B. Faustin (2017). “Mitochondria as Molecular Platforms Integrating Multiple Innate Immune Signalings.” J Mol Biol 429(1): 1-13.

Ouisse, L. H., L. Gautreau-Rolland, M. C. Devilder, M. Osborn, M. Moyon, J. Visentin, F. Halary, M. Bruggemann, R. Buelow, I. Anegon and X. Saulquin (2017). “Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies.” BMC Biotechnol 17(1): 3.

Contis, A., S. Mitrovic, J. Lavie, I. Douchet, E. Lazaro, M. E. Truchetet, C. Goizet, C. Contin-Bordes, T. Schaeverbeke, P. Blanco, R. Rossignol, B. Faustin, C. Richez and P. Duffau (2017). “Neutrophil-derived mitochondrial DNA promotes receptor activator of nuclear factor kappaB and its ligand signalling in rheumatoid arthritis.” Rheumatology (Oxford) 56(7): 1200-1205.

Visentin, J., T. Bachelet, C. Borg, N. Franchini, T. Nong, J. H. Lee, L. Couzi, P. Merville, G. Guidicelli and J. L. Taupin (2017). “Reassessment of T Lymphocytes Crossmatches Results Prediction With Luminex Class I Single Antigen Flow Beads Assay.” Transplantation 101(3): 624-630.

Marlin, R., A. Pappalardo, H. Kaminski, C. R. Willcox, V. Pitard, S. Netzer, C. Khairallah, A. M. Lomenech, C. Harly, M. Bonneville, J. F. Moreau, E. Scotet, B. E. Willcox, B. Faustin and J. Dechanet-Merville (2017). “Sensing of cell stress by human gammadelta TCR-dependent recognition of annexin A2.” Proc Natl Acad Sci U S A 114(12): 3163-3168.

Howard, J., S. Loizon, C. J. Tyler, D. Duluc, B. Moser, M. Mechain, A. Duvignaud, D. Malvy, M. Troye-Blomberg, J. F. Moreau, M. Eberl, O. Mercereau-Puijalon, J. Dechanet-Merville, C. Behr and M. Mamani-Matsuda (2017). “The Antigen-Presenting Potential of Vgamma9Vdelta2 T Cells During Plasmodium falciparum Blood-Stage Infection.” J Infect Dis 215(10): 1569-1579.

Caillard, S., E. Cellot, J. Dantal, O. Thaunat, F. Provot, B. Janbon, M. Buchler, D. Anglicheau, P. Merville, P. Lang, L. Frimat, C. Colosio, E. Alamartine, N. Kamar, A. E. Heng, A. Durrbach, V. Moal, J. Rivalan, I. Etienne, M. N. Peraldi, A. Moreau, B. Moulin and P. R. French (2017). “A French Cohort Study of Kidney Retransplantation after Post-Transplant Lymphoproliferative Disorders.” Clin J Am Soc Nephrol 12(10): 1663-1670.

Di Lorenzo, B., J. Dechanet-Merville and B. Silva-Santos (2017). “Peripheral clonal selection shapes the human gammadelta T-cell repertoire.” Cell Mol Immunol 14(9): 733-735.

2016

Bachelet, T., J. Visentin, G. Guidicelli, P. Merville, L. Couzi and J. L. Taupin (2016). “Anti-HLA donor-specific antibodies are not created equally. Don’t forget the flow.” Transpl Int 29(4): 508-510.

Kaminski, H., L. Couzi, I. Garrigue, J. F. Moreau, J. Dechanet-Merville and P. Merville (2016). “Easier Control of Late-Onset Cytomegalovirus Disease Following Universal Prophylaxis Through an Early Antiviral Immune Response in Donor-Positive, Recipient-Negative Kidney Transplants.” Am J Transplant 16(8): 2384-2394.

Guidicelli, G., F. Guerville, S. Lepreux, C. Wiebe, O. Thaunat, V. Dubois, J. Visentin, T. Bachelet, E. Morelon, P. Nickerson, P. Merville, J. L. Taupin and L. Couzi (2016). “Non-Complement-Binding De Novo Donor-Specific Anti-HLA Antibodies and Kidney Allograft Survival.” J Am Soc Nephrol 27(2): 615-625.

Kaminski, H., I. Garrigue, L. Couzi, B. Taton, T. Bachelet, J. F. Moreau, J. Dechanet-Merville, R. Thiebaut and P. Merville (2016). “Surveillance of gammadelta T Cells Predicts Cytomegalovirus Infection Resolution in Kidney Transplants.” J Am Soc Nephrol 27(2): 637-645.

Loiseau, P., K. Amokhrane, J. Visentin, V. D. Kheav, S. Caillat-Zucman and J. L. Taupin (2016). “Use of Single-Antigen Flow Beads Assays to Assess Anti-HLA Donor-Specific Antibody Strength.” Biol Blood Marrow Transplant 22(2): 394-395.

Turpin, D., M. E. Truchetet, B. Faustin, J. F. Augusto, C. Contin-Bordes, A. Brisson, P. Blanco and P. Duffau (2016). “Role of extracellular vesicles in autoimmune diseases.” Autoimmun Rev 15(2): 174-183.

Visentin, J., L. Minder, J. H. Lee, J. L. Taupin and C. Di Primo (2016). “Calibration free concentration analysis by surface plasmon resonance in a capture mode.” Talanta 148: 478-485.

Visentin, J., G. Guidicelli, L. Couzi, P. Merville, J. H. Lee, C. Di Primo and J. L. Taupin (2016). “Deciphering IgM interference in IgG anti-HLA antibody detection with flow beads assays.” Hum Immunol.

Bachelet, T., P. Merville, J. Dechanet-Merville and L. Couzi (2016). “Cytomegalovirus-Induced gammadelta T Cells During Rejection: An Ambivalent T Cell.” Am J Transplant 16(1): 368-369.

Bachelet, T., C. Martinez, A. Del Bello, L. Couzi, S. Kejji, G. Guidicelli, S. Lepreux, J. Visentin, N. Congy-Jolivet, L. Rostaing, J. L. Taupin, N. Kamar and P. Merville (2016). “Deleterious Impact of Donor-Specific Anti-HLA Antibodies Toward HLA-Cw and HLA-DP in Kidney Transplantation.” Transplantation 100(1): 159-166.

Visentin, J., G. Guidicelli and J. L. Taupin (2016). “Are complement-fixing antibodies against denatured HLA antigens clinically relevant?” Exp Mol Pathol 100(3): 532-533.

Rey, C., B. Faustin, I. Mahouche, R. Ruggieri, C. Brulard, F. Ichas, I. Soubeyran, L. Lartigue and F. De Giorgi (2016). “The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.” Oncogene 35(24): 3190-3200.

Visentin, J., T. Bachelet, C. Borg, N. Franchini, T. Nong, J. H. Lee, L. Couzi, P. Merville, G. Guidicelli and J. L. Taupin (2016). “Reassessment of T Lymphocytes Crossmatches Results Prediction With Luminex Class I Single Antigen Flow Beads Assay.” Transplantation.

Visentin, J., A. Chartier, L. Massara, G. Linares, G. Guidicelli, E. Blanchard, M. Parrens, H. Begueret, C. Dromer and J. L. Taupin (2016). “Lung intragraft donor-specific antibodies as a risk factor for graft loss.” J Heart Lung Transplant.

Visentin, J., D. Ramaharo, A. Ryman, C. Contin-Bordes and P. Merville (2016). “Prevalence of IgA Antibodies to beta2-Glycoprotein I: A Population-Dependent Feature?” Transplantation 100(3): e13-14.

Garcia-Beltran, W. F., A. Holzemer, G. Martrus, A. W. Chung, Y. Pacheco, C. R. Simoneau, M. Rucevic, P. A. Lamothe-Molina, T. Pertel, T. E. Kim, H. Dugan, G. Alter, J. Dechanet-Merville, S. Jost, M. Carrington and M. Altfeld (2016). “Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.” Nat Immunol 17(9): 1067-1074.

Khoryati, L., J. F. Augusto, E. Shipley, C. Contin-Bordes, I. Douchet, S. Mitrovic, M. E. Truchetet, E. Lazaro, P. Duffau, L. Couzi, C. Jacquemin, T. Barnetche, P. Vacher, T. Schaeverbeke, P. Blanco, C. Richez and A. Federation Hospitalo-Universitaire (2016). “IgE Inhibits Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Expression of Interferon-alpha by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus.” Arthritis Rheumatol 68(9): 2221-2231.

2015

Couzi, L., V. Pitard, J. F. Moreau, P. Merville and J. Dechanet-Merville (2015). “Direct and Indirect Effects of Cytomegalovirus-Induced gammadelta T Cells after Kidney Transplantation.” Front Immunol 6: 3.

Kabelitz, D. and J. Dechanet-Merville (2015). “Editorial: “Recent Advances in Gamma/Delta T Cell Biology: New Ligands, New Functions, and New Translational Perspectives”.” Front Immunol 6: 371.

Viot, B., I. Garrigue, B. Taton, T. Bachelet, J. F. Moreau, J. Dechanet-Merville, P. Merville and L. Couzi (2015). “Two-year post-transplantation cytomegalovirus DNAemia in asymptomatic kidney transplant recipients: incidence, risk factors, and outcome.” Transpl Infect Dis 17(4): 497-509.

Visentin, J., G. Guidicelli and J. L. Taupin (2015). “Assessing HLA Antibody Strength: Have We Thought About Everything?” Am J Transplant 15(12): 3271.

Sicard, A., S. Ducreux, M. Rabeyrin, L. Couzi, B. McGregor, L. Badet, J. Y. Scoazec, T. Bachelet, S. Lepreux, J. Visentin, P. Merville, V. Fremeaux-Bacchi, E. Morelon, J. L. Taupin, V. Dubois and O. Thaunat (2015). “Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss.” J Am Soc Nephrol 26(2): 457-467.

Bonneville, M., Z. W. Chen, J. Dechanet-Merville, M. Eberl, J. J. Fournie, J. M. Jameson, R. D. Lopez, M. Massaia and B. Silva-Santos (2015). “Chicago 2014–30 years of gammadelta T cells.” Cell Immunol 296(1): 3-9.

Couzi, L., R. Perera, M. Manook, A. N. Barnett, O. Shaw, N. Kessaris, S. D. Marks, A. Dorling and N. Mamode (2015). “Incidence and Outcome of C4d Staining With Tubulointerstitial Inflammation in Blood Group-incompatible Kidney Transplantation.” Transplantation 99(7): 1487-1494.

Visentin, J., G. Guidicelli, J. F. Moreau, J. H. Lee and J. L. Taupin (2015). “Deciphering allogeneic antibody response against native and denatured HLA epitopes in organ transplantation.” Eur J Immunol 45(7): 2111-2121.

Jacquemin, C., N. Schmitt, C. Contin-Bordes, Y. Liu, P. Narayanan, J. Seneschal, T. Maurouard, D. Dougall, E. S. Davizon, H. Dumortier, I. Douchet, L. Raffray, C. Richez, E. Lazaro, P. Duffau, M. E. Truchetet, L. Khoryati, P. Mercie, L. Couzi, P. Merville, T. Schaeverbeke, J. F. Viallard, J. L. Pellegrin, J. F. Moreau, S. Muller, S. Zurawski, R. L. Coffman, V. Pascual, H. Ueno and P. Blanco (2015). “OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response.” Immunity 42(6): 1159-1170.

Kolev, M., S. Dimeloe, G. Le Friec, A. Navarini, G. Arbore, G. A. Povoleri, M. Fischer, R. Belle, J. Loeliger, L. Develioglu, G. R. Bantug, J. Watson, L. Couzi, B. Afzali, P. Lavender, C. Hess and C. Kemper (2015). “Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.” Immunity 42(6): 1033-1047.

Khairallah, C., S. Netzer, A. Villacreces, M. Juzan, B. Rousseau, S. Dulanto, A. Giese, P. Costet, V. Praloran, J. F. Moreau, P. Dubus, D. Vermijlen, J. Dechanet-Merville and M. Capone (2015). “gammadelta T cells confer protection against murine cytomegalovirus (MCMV).” PLoS Pathog 11(3): e1004702.

Bachelet, T., C. Nodimar, J. L. Taupin, S. Lepreux, K. Moreau, D. Morel, G. Guidicelli, L. Couzi and P. Merville (2015). “Intravenous immunoglobulins and rituximab therapy for severe transplant glomerulopathy in chronic antibody-mediated rejection: a pilot study.” Clin Transplant 29(5): 439-446.

Guerville, F., S. Daburon, R. Marlin, L. Lartigue, S. Loizon, V. Pitard, L. Couzi, J. F. Moreau, J. Dechanet-Merville and B. Faustin (2015). “TCR-dependent sensitization of human gammadelta T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance.” Oncoimmunology 4(5): e1003011.

Visentin, J., M. Marroc, G. Guidicelli, T. Bachelet, T. Nong, J. F. Moreau, J. H. Lee, P. Merville, L. Couzi and J. L. Taupin (2015). “Clinical impact of preformed donor-specific denatured class I HLA antibodies after kidney transplantation.” Clin Transplant 29(5): 393-402.

Kaminski, H., L. Couzi, J. Dechanet-Merville and P. Merville (2015). “[Immunomonitoring for cytomegalovirus infection in kidney transplantation: Development and prospects].” Nephrol Ther 11(6): 465-473.

Petitpierre, F., F. Cornelis, L. Couzi, A. S. Lasserre, E. Tricaud, Y. Le Bras, P. Merville, C. Combe, J. M. Ferriere and N. Grenier (2015). “Embolization of renal arteries before transplantation in patients with polycystic kidney disease: a single institution long-term experience.” Eur Radiol 25(11): 3263-3271.

Queruel, V., R. Kabore, A. Guillaume, K. Moreau, K. Leffondre, L. Couzi, A. Quinart, J. Rogier, P. Tauzin-Fin, P. Merville, G. Robert, G. Pasticier, H. Bensadoun, J. Ferriere and J. Bernhard (2015). “[Not Available].” Prog Urol 25(13): 764-765.

Couzi, L., M. Manook, R. Perera, O. Shaw, Z. Ahmed, N. Kessaris, A. Dorling and N. Mamode (2015). “Difference in outcomes after antibody-mediated rejection between abo-incompatible and positive cross-match transplantations.” Transpl Int 28(10): 1205-1215.

Guenot, M., S. Loizon, J. Howard, G. Costa, D. A. Baker, S. Y. Mohabeer, M. Troye-Blomberg, J. F. Moreau, J. Dechanet-Merville, O. Mercereau-Puijalon, M. Mamani-Matsuda and C. Behr (2015). “Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vgamma9Vdelta2 T Cells.” Infect Immun 83(10): 3816-3824.

Krzywinska, E., N. Allende-Vega, A. Cornillon, D. N. Vo, L. Cayrefourcq, C. Panabieres, C. Vilches, J. Dechanet-Merville, Y. Hicheri, J. F. Rossi, G. Cartron and M. Villalba (2015). “Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers.” EBioMedicine 2(10): 1364-1376.

Neau-Cransac, M., B. Le Bail, G. Guidicelli, J. Visentin, K. Moreau, A. Quinart, A. Boueilh, C. Laurent and J. L. Taupin (2015). “Evolution of serum and intra-graft donor-specific anti-HLA antibodies in a patient with two consecutive liver transplantations.” Transpl Immunol 33(2): 58-62.

Visentin, J., G. Guidicelli, T. Nong, J. F. Moreau, P. Merville, L. Couzi, J. H. Lee and J. L. Taupin (2015). “Evaluation of the iBeads assay as a tool for identifying class I HLA antibodies.” Hum Immunol 76(9): 651-656.

2016

Gensous, N., N. Schmitt, C. Richez, H. Ueno and P. Blanco (2016). “T follicular helper cells, interleukin-21 and systemic lupus erythematosus.” Rheumatology (Oxford).

Blanco, P., H. Ueno and N. Schmitt (2016). “T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis.” Eur J Immunol 46(2): 281-290.

Contis, A., H. Vanquaethem, M. E. Truchetet, L. Couzi, C. Rigothier, C. Richez, E. Lazaro and P. Duffau (2016). “Analysis of the effectiveness and safety of rituximab in patients with refractory lupus nephritis: a chart review.” Clin Rheumatol 35(2): 517-522.

Schaeverbeke, T., M. E. Truchetet, M. Kostine, T. Barnetche, B. Bannwarth and C. Richez (2016). “Immunogenicity of biologic agents in rheumatoid arthritis patients: lessons for clinical practice.” Rheumatology (Oxford) 55(2): 210-220.

Turpin, D., M. E. Truchetet, B. Faustin, J. F. Augusto, C. Contin-Bordes, A. Brisson, P. Blanco and P. Duffau (2016). “Role of extracellular vesicles in autoimmune diseases.” Autoimmun Rev 15(2): 174-183.

Kostine, M., O. Lichtwitz, M. E. Truchetet and N. Leveziel (2016). “Choroidal osteoma: Bone in the eye.” Joint Bone Spine 83(4): 454.

Poissonnier, A., D. Sanseau, M. Le Gallo, M. Malleter, N. Levoin, R. Viel, L. Morere, A. Penna, P. Blanco, A. Dupuy, F. Poizeau, A. Fautrel, J. Seneschal, F. Jouan, J. Ritz, E. Forcade, N. Rioux, C. Contin-Bordes, T. Ducret, A. M. Vacher, P. A. Barrow, R. J. Flynn, P. Vacher and P. Legembre (2016). “CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.” Immunity 45(1): 209-223.

Schmitt, N., Y. Liu, S. E. Bentebibel and H. Ueno (2016). “Molecular Mechanisms Regulating T Helper 1 versus T Follicular Helper Cell Differentiation in Humans.” Cell Rep 16(4): 1082-1095.

Darrigade, A. S., A. L. Vedie, C. Gauthier, M. Cario-Andre, A. Taieb, M. E. Truchetet, J. Constans and J. Seneschal (2016). “Pigmented skin patches without scleroderma as a predominant clinical symptom revealing systemic sclerosis.” Clin Exp Dermatol 41(4): 379-382.

Scherlinger, M., T. Schaeverbeke, P. Blanco and C. Richez (2016). “A unilateral erosive arthritis in a patient with systemic lupus erythematosus.” Joint Bone Spine.

Truchetet, M. E., N. Poursac, T. Barnetche, E. Shipley, J. E. Gottenberg, B. Bannwarth, C. Richez and T. Schaeverbeke (2016). “Abatacept monotherapy compared with abatacept plus disease-modifying anti-rheumatic drugs in rheumatoid arthritis patients: data from the ORA registry.” Arthritis Res Ther 18: 72.

Bentebibel, S. E., S. Khurana, N. Schmitt, P. Kurup, C. Mueller, G. Obermoser, A. K. Palucka, R. A. Albrecht, A. Garcia-Sastre, H. Golding and H. Ueno (2016). “ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination.” Sci Rep 6: 26494.

Truchetet, M. E., B. Demoures, J. Eduardo Guimaraes, A. Bertrand, P. Laurent, V. Jolivel, I. Douchet, C. Jacquemin, L. Khoryati, P. Duffau, E. Lazaro, C. Richez, J. Seneschal, M. S. Doutre, J. L. Pellegrin, J. Constans, T. Schaeverbeke, P. Blanco, C. Contin-Bordes and A. Federation Hospitalo-Universitaire (2016). “Platelets Induce Thymic Stromal Lymphopoietin Production by Endothelial Cells: Contribution to Fibrosis in Human Systemic Sclerosis.” Arthritis Rheumatol 68(11): 2784-2794.

Brembilla, N. C., A. M. Dufour, M. Alvarez, S. Hugues, E. Montanari, M. E. Truchetet, P. Lonati, L. Fontao, A. Gabrielli, S. Vettori, G. Valentini, W. H. Boehncke, P. Meroni and C. Chizzolini (2016). “IL-22 capacitates dermal fibroblast responses to TNF in scleroderma.” Ann Rheum Dis 75(9): 1697-1705.

Khoryati, L., J. F. Augusto, E. Shipley, C. Contin-Bordes, I. Douchet, S. Mitrovic, M. E. Truchetet, E. Lazaro, P. Duffau, L. Couzi, C. Jacquemin, T. Barnetche, P. Vacher, T. Schaeverbeke, P. Blanco, C. Richez and A. Federation Hospitalo-Universitaire (2016). “IgE Inhibits Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Expression of Interferon-alpha by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus.” Arthritis Rheumatol 68(9): 2221-2231.

Puges, M., P. Biscay, T. Barnetche, M. E. Truchetet, C. Richez, J. Seneschal, N. Gensous, E. Lazaro and P. Duffau (2016). “Immunogenicity and impact on disease activity of influenza and pneumococcal vaccines in systemic lupus erythematosus: a systematic literature review and meta-analysis.” Rheumatology (Oxford) 55(9): 1664-1672.

Lazaro, E., M. Scherlinger, M. E. Truchetet, L. Chiche, T. Schaeverbeke, P. Blanco and C. Richez (2016). “Biotherapies in systemic lupus erythematosus: New targets.” Joint Bone Spine.

2014-2015

Bentebibel, S. E., C. Jacquemin, N. Schmitt and H. Ueno (2015). “Analysis of human blood memory T follicular helper subsets.” Methods Mol Biol 1291: 187-197.

Raffray, L., I. Douchet, J. F. Augusto, J. Youssef, C. Contin-Bordes, C. Richez, P. Duffau, M. E. Truchetet, J. F. Moreau, C. Cazanave, L. Leroux, G. Mourrissoux, F. Camou, B. Clouzeau, P. Jeannin, Y. Delneste, C. Gabinski, O. Guisset, E. Lazaro and P. Blanco (2015). “Septic shock sera containing circulating histones induce dendritic cell-regulated necrosis in fatal septic shock patients.” Crit Care Med 43(4): e107-116.

Cornelis, F., M. E. Truchetet, N. Amoretti, D. Verdier, C. Fournier, O. Pillet, O. Gille and O. Hauger (2014). “Bisphosphonate therapy for unresectable symptomatic benign bone tumors: a long-term prospective study of tolerance and efficacy.” Bone 58: 11-16.

Schmitt, N. and H. Ueno (2015). “Regulation of human helper T cell subset differentiation by cytokines.” Curr Opin Immunol 34: 130-136.

Jacquemin, C., N. Schmitt, C. Contin-Bordes, Y. Liu, P. Narayanan, J. Seneschal, T. Maurouard, D. Dougall, E. S. Davizon, H. Dumortier, I. Douchet, L. Raffray, C. Richez, E. Lazaro, P. Duffau, M. E. Truchetet, L. Khoryati, P. Mercie, L. Couzi, P. Merville, T. Schaeverbeke, J. F. Viallard, J. L. Pellegrin, J. F. Moreau, S. Muller, S. Zurawski, R. L. Coffman, V. Pascual, H. Ueno and P. Blanco (2015). “OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response.” Immunity 42(6): 1159-1170.

Richez, C., M. E. Truchetet, T. Schaeverbeke and B. Bannwarth (2014). “Atacicept as an investigated therapy for rheumatoid arthritis.” Expert Opin Investig Drugs 23(9): 1285-1294.

Schmitt, N., Y. Liu, S. E. Bentebibel, I. Munagala, L. Bourdery, K. Venuprasad, J. Banchereau and H. Ueno (2014). “The cytokine TGF-beta co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells.” Nat Immunol 15(9): 856-865.

Schmitt, N., S. E. Bentebibel and H. Ueno (2014). “Phenotype and functions of memory Tfh cells in human blood.” Trends Immunol 35(9): 436-442.

Bertrand, A., M. Kostine, T. Barnetche, M. E. Truchetet and T. Schaeverbeke (2015). “Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis.” BMC Med 13: 211.

2016

Alizadeh, D. and N. Larmonier (2016). “Generation and Expansion of T Helper 17 Lymphocytes Ex Vivo.” Methods Mol Biol 1371: 101-113.

Stokes, J., E. A. Hoffman, Y. Zeng, N. Larmonier and E. Katsanis (2016). “Post-transplant bendamustine reduces GvHD while preserving GvL in experimental haploidentical bone marrow transplantation.” Br J Haematol 174(1): 102-116.

Yin, W., L. Gorvel, S. Zurawski, D. Li, L. Ni, D. Duluc, K. Upchurch, J. Kim, C. Gu, R. Ouedraogo, Z. Wang, Y. Xue, H. Joo, J. P. Gorvel, G. Zurawski and S. Oh (2016). “Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8(+) and CD4(+) T Cells.” EBioMedicine 5: 46-58.

Yin, W., D. Duluc, H. Joo, Y. Xue, C. Gu, Z. Wang, L. Wang, R. Ouedraogo, L. Oxford, A. Clark, F. Parikh, S. Kim-Schulze, L. Thompson-Snipes, S. Y. Lee, C. Beauregard, J. H. Woo, S. Zurawski, A. G. Sikora, G. Zurawski and S. Oh (2016). “Therapeutic HPV Cancer Vaccine Targeted to CD40 Elicits Effective CD8+ T-cell Immunity.” Cancer Immunol Res 4(10): 823-834.

2014-2015

Duluc, D., R. Banchereau, J. Gannevat, L. Thompson-Snipes, J. P. Blanck, S. Zurawski, G. Zurawski, S. Hong, J. Rossello-Urgell, V. Pascual, N. Baldwin, J. Stecher, M. Carley, M. Boreham and S. Oh (2014). “Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments.” Genome Med 6(11): 98.

Janikashvili, N., T. Chikovani, S. Audia, B. Bonnotte and N. Larmonier (2015). “T Lymphocyte Plasticity in Autoimmunity and Cancer.” Biomed Res Int 2015: 540750.

Majeed, B. A., L. S. Eberson, S. Tawinwung, N. Larmonier, T. W. Secomb and D. F. Larson (2015). “Functional aortic stiffness: role of CD4(+) T lymphocytes.” Front Physiol 6: 235.

Majeed, B., S. Tawinwung, L. S. Eberson, T. W. Secomb, N. Larmonier and D. F. Larson (2014). “Interleukin-2/Anti-Interleukin-2 Immune Complex Expands Regulatory T Cells and Reduces Angiotensin II-Induced Aortic Stiffening.” Int J Hypertens 2014: 126365.

Hanke, N. T., C. J. LaCasse, C. B. Larmonier, D. Alizadeh, M. Trad, N. Janikashvili, B. Bonnotte, E. Katsanis and N. Larmonier (2014). “PIAS1 and STAT-3 impair the tumoricidal potential of IFN-gamma-stimulated mouse dendritic cells generated with IL-15.” Eur J Immunol 44(8): 2489-2499.

Parikh, F., D. Duluc, N. Imai, A. Clark, K. Misiukiewicz, M. Bonomi, V. Gupta, A. Patsias, M. Parides, E. G. Demicco, D. Y. Zhang, S. Kim-Schulze, J. Kao, S. Gnjatic, S. Oh, M. R. Posner and A. G. Sikora (2014). “Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer.” Cancer Res 74(24): 7205-7216.

Alizadeh, D., M. Trad, N. T. Hanke, C. B. Larmonier, N. Janikashvili, B. Bonnotte, E. Katsanis and N. Larmonier (2014). “Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer.” Cancer Res 74(1): 104-118.

Alizadeh, D., E. Katsanis and N. Larmonier (2014). “Chemotherapeutic targeting of myeloid-derived suppressor cells.” Oncoimmunology 3(1): e27359.

Janikashvili, N., M. Trad, A. Gautheron, M. Samson, B. Lamarthee, F. Bonnefoy, S. Lemaire-Ewing, M. Ciudad, K. Rekhviashvili, F. Seaphanh, B. Gaugler, S. Perruche, A. Bateman, L. Martin, S. Audia, P. Saas, N. Larmonier and B. Bonnotte (2015). “Human monocyte-derived suppressor cells control graft-versus-host disease by inducing regulatory forkhead box protein 3-positive CD8+ T lymphocytes.” J Allergy Clin Immunol 135(6): 1614-1624 e1614.

Duluc, D., H. Joo, L. Ni, W. Yin, K. Upchurch, D. Li, Y. Xue, P. Klucar, S. Zurawski, G. Zurawski and S. Oh (2014). “Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1.” J Immunol 192(12): 5776-5788.

Alizadeh, D. and N. Larmonier (2014). “Chemotherapeutic targeting of cancer-induced immunosuppressive cells.” Cancer Res 74(10): 2663-2668.

Joo, H., D. Li, M. Dullaers, T. W. Kim, D. Duluc, K. Upchurch, Y. Xue, S. Zurawski, R. Le Grand, Y. J. Liu, M. Kuroda, G. Zurawski and S. Oh (2014). “C-type lectin-like receptor LOX-1 promotes dendritic cell-mediated class-switched B cell responses.” Immunity 41(4): 592-604.

Miot, C., E. Beaumont, D. Duluc, H. Le Guillou-Guillemette, L. Preisser, E. Garo, S. Blanchard, I. Hubert Fouchard, C. Creminon, P. Lamourette, I. Fremaux, P. Cales, F. Lunel-Fabiani, J. Boursier, O. Braum, H. Fickenscher, P. Roingeard, Y. Delneste and P. Jeannin (2015). “IL-26 is overexpressed in chronically HCV-infected patients and enhances TRAIL-mediated cytotoxicity and interferon production by human NK cells.” Gut 64(9): 1466-1475.

2018