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Poste  d’Assistant Ingénieur dans le domaine de l’immunologie Missions et activités : Sous la responsabilité d’un chercheur, le candidat -préparera ses expériences suivant des procédures établies-réalisera les expériences-analysera et interprètera ses résultats -discutera et présentera ses résultats-participera aux activités générales du laboratoire Compétences requises : Niveau BAC +2-Expérience avec l’expérimentationanimale-Connaissances approfondies en biologie cellulaire/immunologie-Maitrise de… Read more »

By S.Paludan, T.Pradeu, S.Masters & T.Mogensen. Abstract The immune system enables organisms to combat infections and to eliminate endogenous challenges. Immune responses can be evoked through diverse inducible pathways. However, various constitutive mechanisms are also required for immunocompetence. The inducible responses of pattern recognition receptors of the innate immune system and antigen-specific receptors of the… Read more »

Characterization of a unique γδ T cell subset as a specific marker of CMV infection severity Abstract Cytomegalovirus is a major infectious cause of mortality and morbidity following transplantation. We have previously demonstrated that the tissue-associated adaptive Vδ2neg γδ T-cells are key effectors responding to CMV and associated to recovery, contrasting with their innate-like circulating… Read more »

Vanja Sisirak is currently inviting applications from enthusiastic postdoctoral candidates to join his team to study how the immune system controls tumor development. The position is supported by the funding from the Siric BRIO program and is available for a 12-month period starting on September 2020, with the possibility for extension. Further information available here…. Read more »

Many of our Master and PhD students (Arthur Lacapère, Damien Leleu, Florent Guerville, Florent Peyraud, Gaël Galli, Hadrien Golhen, Hannah Kaminski, Laura Barthod, Marie-Caroline Haudiquet) in the lab have been involved in different tasks launched during the COVID-19 crisis: -The “city-hospital”call platform to respond to general practitioners (plateforme VILLHOP) -SARS-CoV-2 testing in care homes and… Read more »

Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA The latest work of Vanja Sisirak together with Boris Reizis identifying how plasmacytoid dendritic cells and type I Interferons promote extra follicular B cell responses to extracellular self-DNA in Dnase1L3 deficient mice and consequently exacerbate lupus pathogenesis. See the article… Read more »

A project led by a young, tenured solid organ transplant (SOT) researcher from ImmunoConcEpT laboratory, Dr. Jonathan Visentin, has been awarded by an EU’s Marie Sklodowska-Curie Actions Global Fellowship (MSCA-GF). This 3 year project is called “DABAT” (DNA-sensing by AIM2 in activated B cells: novel targets to improve Allogeneic haematopoietic stem cell Transplantation, grant number… Read more »

Uncovering the Anticancer Potential of Murine Cytomegalovirus against Human Colon Cancer Cells. Massara Layal, Khairallah Camille, Yared Nathalie, Pitard Vincent, Rousseau Benoit, Izotte Julien, Giese Alban, Dubus Pierre, Gauthereau Xavier, Déchanet-Merville Julie, Capone Myriam. Molecular Therapy Oncolytics Abstract Human cytomegalovirus (HCMV) components are often found in tumors, but the precise relationship between HCMV and cancer… Read more »

Position as Associate Professor at the University of Bordeaux AOS: Philosophy of medicine, Philosophy of biology AOC: Philosophy of Science University of Bordeaux (France) Deadline for application: March 9, 2020. Application: mael.lemoine@u-bordeaux.fr Short description of the job profile Candidates will have developed an expertise in any topic of medical science (e.g. a disease, a method,… Read more »

The Thomas Pradeu’s short book Philosophy of Immunology just came out at Cambridge University Press, and is freely available in open access:https://www.cambridge.org/core/elements/philosophy-of-immunology/06F0C341035299674EECF0406E5D8E31