Who am I ?
Dr. Maya Saleh obtained a Ph. D. in Biochemistry in 2001 from McGill University, where she studied mechanisms of transcriptional regulation in embryonic development. In 2002, she joined Merck Research Laboratories in Montreal to study apoptosis regulation in neurodegeneration and sepsis, and in 2004, moved to the La Jolla Institute for Allergy and Immunology in San Diego, California, to investigate mechanisms of innate immunity in host defense. Dr. Saleh joined the Faculty of Medicine at McGill University in 2005, and currently holds the positions of Associate Professor of Medicine and Director of the Inflammation and Cancer Program. She is a McGill University Dawson Scholar, a Fonds de Recherche du Québec – Santé (FRQS) Chercheur-Boursier Senior Investigator and a Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease.
> My work
Dr. Saleh’s research group investigates the fundamental biology of the innate immune system as well as the regulation of innate immunity and cell death pathways in immune-mediated inflammatory diseases and cancer, with the goal of identifying novel therapeutic targets for these applications. Her team has focused on dissecting the complex molecular mechanisms used by intracellular sensors to detect microbial products or host-derived danger signals in these conditions and the downstream effector mechanisms that restore homeostasis or promote disease states. Her research program has contributed to the inflammasome field and has implicated the inflammasome in several infectious, inflammatory and metabolic diseases, and more recently in cancer progression and anti-tumor immunity.