Sébastien BRIAS

Who am I ?
I am a M2 student under the direction of Dr.Myriam Capone.

> My projects in Immuno ConcEpT
The group of Julie Dechanet Merville has demonstrated the participation of γδ T lymphocytes (γδ  TL) in the immune response against both human and murine cytomegalovirus (CMV). The group also showed a correlation between seropositive kidney transplant recipient with good rates of γδ  TL and lower risk of developing several cancers (Couzi et al, JASN, 2010). Interestingly, γδ  TL are the strongest factor for good prognosis in cancer (Gentles et al, Nat Med., 2015) , but recent studies showed that they can both play anti and pro-tumoral roles depending on the context (reviewed in Silva-Santos et al, Nat Rev Immunol., 2015). My project consist in determining the reactivity against cancer of CMV-primed γδ  TL using mouse model of CMV and transplantable mouse breast cancer and melanoma.

> E-mail me here : sbrias@immuconcept.org or briassebastien@gmail.com

> Other: Linkedin