Thomas PAZ DEL SOCORRO
Who am I ?
I am an M2 Microbiology-Immunology student under the direction of Christophe Richez
> My projects in Immuno ConcEpT
> My current project in….
The group of Patrick Blanco have shown that platelets-derived microparticules are increased in the context of systemic lupus. Moreover, they show that platelets are activated in patient with lupus and that activation is characterized by an overexpression of P-selectin. Finally, P-selectin seems to interact with PSGL-1 on regulatory T cell surface and this interaction inhibit Treg activity.
We seek to confirm these results using model mice (« lupus-mice » and « WT »). We will try to reproduce experiments in mice. Finally, we want to blockade P-selectin to see if there is a impact on lupus pathogenesis.
> E-mail me here : firstname.lastname@example.org
> Other: Linkedin
Phone number: +336 62 22 28 51